Reflux symptoms with a normal endoscopy and poor PPI response: what is worth clarifying?

A normal endoscopy does not by itself tell you whether symptoms are caused by acid reflux, non-acid reflux, esophageal sensitivity, eosinophilic inflammation, motility or another mechanism. Answer three quick questions to explore what may deserve attention next.

QUESTION 1 OF 3

What persists despite acid-reflux treatment?

Choose the closest match; you can start over if the situation changes.

Why this matters

The first answer determines which evidence pathway we explain first. The options are prompts for discussion, not a diagnosis.